16th Sound and Music Computing Conference SMC 2019 (28–31 May 2019, Malaga, Spain)

The 16th Sound and Music Computing Conference (SMC 2019) took place in Malaga, Spain, 28-31 May 2019 and it was organized by the Application of Information and Communication Technologies Research group (ATIC) of the University of Malaga (UMA). The SMC 2019 associated Summer School took place 25-28 May 2019. The First International Day of Women in Inclusive Engineering, Sound and Music Computing Research (WiSMC 2019) took place on 28 May 2019. The SMC 2019 TOPICS OF INTEREST included a wide selection of topics related to acoustics, psychoacoustics, music, technology for music, audio analysis, musicology, sonification, music games, machine learning, serious games, immersive audio, sound synthesis, etc

Alteration and Oxidiation of an Olivine Lamprophyre Dike from Southern Utah, USA: An Analog for Mars

We report on oxidized basaltic dike intrusions on the Colorado Plateau as analog for Martian basalt oxidation

Molecular and all solid DFT studies of the magnetic and chemical bonding properties within KM[Cr(CN)6_6] (M = V, Ni) complexes

A study at both the molecular and extended solid level in the framework DFT is carried out for KM[Cr(CN)$_6$] (M = V, Ni). From molecular calculations, the exchange parameters J are obtained, pointing to the expected magnetic ground states, i.e., antiferromagnetic for M = V with J = -296.5 cm$^{-1}$ and ferromagnetic for M = Ni with J = +40.5 cm$^{-1}$. From solid state computations the same ground states and J magnitudes are confirmed from energy differences. Furthermore an analysis of the site projected density of states and of the chemical bonding is developed in which the cyanide ion linkage is analyzed addressing some isomerism aspects.Comment: new results, 5 tables, 7 fig

Wearable sensors system for an improved analysis of freezing of gait in Parkinson's disease using electromyography and inertial signals

We propose a wearable sensor system for automatic, continuous and ubiquitous analysis of Freezing of Gait (FOG), in patients affected by Parkinson's disease. FOG is an unpredictable gait disorder with different clinical manifestations, as the trembling and the shuffling-like phenotypes, whose underlying pathophysiology is not fully understood yet. Typical trembling-like subtype features are lack of postural adaptation and abrupt trunk inclination, which in general can increase the fall probability. The targets of this work are detecting the FOG episodes, distinguishing the phenotype and analyzing the muscle activity during and outside FOG, toward a deeper insight in the disorder pathophysiology and the assessment of the fall risk associated to the FOG subtype. To this aim, gyroscopes and surface electromyography integrated in wearable devices sense simultaneously movements and action potentials of antagonist leg muscles. Dedicated algorithms allow the timely detection of the FOG episode and, for the first time, the automatic distinction of the FOG phenotypes, which can enable associating a fall risk to the subtype. Thanks to the possibility of detecting muscles contractions and stretching exactly during FOG, a deeper insight into the pathophysiological underpinnings of the different phenotypes can be achieved, which is an innovative approach with respect to the state of art

Tradition et modernité à la Faculté de droit de l'Université Laval de 1945 à 1965

Durant deux décennies, soit de 1945 à 1965, la Faculté de droit de l'Université Laval connaît une évolution marquante. Au début de la période, la Faculté est caractérisée par un attachement à la tradition. Les quelques velléités de changement qui se manifestent sont farouchement combattues. À la Révolution tranquille, alors que la société québécoise vit une mutation, la Faculté est l'objet d'une remise en question globale. Sous la pression des étudiants, qui bénéficient d'un important appui populaire, les autorités facultaires doivent alors accepter des changements profonds.For two decades—from 1945 to 1965 — the Laval University Law Faculty was to undergo profounds changes. At the outset, the school was shrouded in a veil of tradition and whatever hints of change to be manifested were fiercely combatted. With the onset of the Quiet Revolution, when Quebec society itself was in profound transition, the law Faculty becomes the subject of indepth questioning. Under pressure from the student body — which benefitted from widespread popular support—Faculty authorities were to acquiesce to substantial changes

From bench to bountiful harvests : a road map for the next decade of Arabidopsis research

In the face of an increasing world population and climate instability, the demands for food and fuel will continue to rise. Plant science will be crucial to help meet these exponentially increasing requirements for food and fuel supplies. Fundamental plant research will play a major role in providing key advances in our understanding of basic plant processes that can then flow into practical advances through knowledge sharing and collaborations. The model plant Arabidopsis thaliana has played a major role in our understanding of plant biology, and the Arabidopsis community has developed many tools and resources to continue building on this knowledge. Drawing from previous experience of internationally coordinated projects, The international Arabidopsis community, represented by the Multinational Arabidopsis Steering Committee (MASC), has drawn up a road map for the next decade of Arabidopsis research to inform scientists and decision makers on the future foci of Arabidopsis research within the wider plant science landscape. This article provides a summary of the MASC road map

Le contrôle de la discrimination raciale au Canada

This article is divided into four parts: the first is a brief survey of race relations in Canada before the enactment of anti-discrimination legislation; the next two parts are devoted to an outline of the scope of this legislation and of the administration and enforcement of it ; finally, the last part suggests some current and possible future developments to make it more effective. Prior to the nineteenth century both the French and the British settlers in the colonies that have become a part of Canada had slaves. Slavery was not, however, very extensive due to lack of large agricultural holdings. At the end of the eighteenth century the legislature in Upper Canada and some judges in Lower Canada limited its expansion and helped to end its practice. The British Imperial Emancipation Act of 1833 brought it to an end. In the next few decades, up to the American Civil War, some Canadians helped run-away slaves from the slave-holding states in the United States, while others actively discouraged them from coming. By the end of the nineteenth century a new source of racial tension arose on the West Coast between the newer immigrants from Asia and the older immigrants from Europe. The result was the enactment of numerous discriminatory laws by the legislature of British Columbia and subsequently, on a lesser scale, by the other western provinces. Most of these remained on the statute books until after World War II. None of these laws were held invalid by the courts on the basis of their discriminatory nature. In addition, both the common law and the Civil Code were interpreted as not prohibiting private discrimination, except by hotel-keepers and common carriers. The change from this situation started in the I930's with a few specific legislative prohibitions of discrimination in specific instances. In the 1940's Ontario, with respect to signs and advertisements and Saskatchewan, with respect to a whole range of activities, enacted legislation prohibiting discrimination, enforcing their prohibitions with penal sanctions. The 1950's saw the introduction of fair employment and fair accommodation practices acts. By the I960's these were being consolidated into comprehensive human rights codes administered by human rights commissions. This trend has continued up to this year, with the result that all eleven jurisdictions have commissions charged with enforcing antidiscrimination codes or acts. The usual, but not invariable, procedure is the laying of a complaint, the investigation of it by the commission staff, an attempt to bring about a settlement and finally, failing that, a hearing before an adjudicative tribunal to determine whether an act of discrimination did occur and, if so, what redress is appropriate. In concluding, three suggestions are made regarding measures that could be taken to strengthen the effectiveness of anti-discrimination legislation: (I) contract compliance; (2) greater independence for the commissions from the government; and (3) giving the legislation paramountcy over other statutes

MAIT cells come to the rescue in cancer immunotherapy?

Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells. Invariant T cells are characterized by T cell receptors recognizing a limited range of non-peptide antigens, presented only in the context of particular molecules. Mucosal-associated invariant T cells (MAIT cells) are an example of such unconventional cells. In humans, they constitute between 1% and 8% of the peripheral blood T lymphocytes and are further enriched in mucosal tissues, mesenteric lymph nodes, and liver, where they can account for even 40% of all the T cells. MAIT cells recognize antigens in the context of major histocompatibility complex class I-related protein (MR1). Upon activation, they instantly release pro-inflammatory cytokines and mediate cytolytic function towards bacterially infected cells. As such, they have been a rapidly evolving research topic not only in the field of infectious diseases but also in the context of many chronic inflammatory diseases and, more recently, in immuno-oncology. Novel findings suggest that MAIT cells function could also be modulated by endogenous ligands and drugs, making them an attractive target for therapeutic approaches. In this review, we summarize the current understanding of MAIT cell biology, their role in health and disease and discuss their future potential in cancer immunotherapy. This is discussed through the prism of knowledge and experiences with invariant natural killer T cells (iNKT)—another prominent unconventional T cell subset that shares many features with MAIT cells

HDE 269896: una supergigante especial de la nube mayor de Magallanes

The star HDE 269896, a hypergiant in the Large Magellanic Cloud, with spectral type ON9.7 Ia+, is a special case within the known OB Zoo. We have discovered strong emission from the N II 5000 ˚A complex in its spectrum, and the previously known He II λ4686 emission, with an anomalous strength for the spectral type, has also been observed. Comparing HDE 269896 with other objects that show N II emission lines, such as WN10 and WN11 types, we find that this star is highly evolved, albeit less so than the latter stars. Thus, it is reasonable to propose that HDE 269896 should be in an immediate pre-WNVL (Very Late WN) state. Another characteristic of this star is the unusually wide range of ionization present in its extended atmosphere. Subsequent analysis of its spectrum will permit a better understanding of both the relevant atomic physics and the structure of this unusual atmosphere.La estrella HDE 269896, hipergigante de la Nube Mayor de Magallanes, con tipo espectral ON9.7 Ia+, es un caso particular dentro del zoológico OB conocido. Hemos encontrado en su espectro, una intensa emisión del complejo N II 5000 A y se ha observado también una emisión ˚ de He II λ4686, la cual por su intensidad, resulta anómala para su tipo espectral. Comparando a HDE 269896 con otros objetos que muestran líneas de emisión de N II, como ser WN10 y WN11, resulta evidente que HDE 269896 es un objeto altamente evolucionado, aunque lo es menos que las estrellas WN10 y WN11. Por esto, resulta razonable proponer que HDE 269896 debe hallarse en un estado inmediato de pre-WNVL (Very Late WN). Otra particularidad presente en HDE 269896, es el inusualmente amplio rango de ionización que tiene lugar en su atmósfera extendida. Análisis posteriores de su espectro permitirán comprender mejor tanto la física atómica involucrada como la estructura de esta atmósfera inusual.Fil: Corti, Mariela Alejandra. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomia; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Walborn, Nolan Revere. Space Telescope Science Institute; Estados Unido